This study explores making communication a discipline defined by the science of meaning. The change would strengthen the identification and feasibility of the communication field and provide a baseline for developing core communication knowledge. This study proposes an analytical framework of the science of meaning to facilitate internal dialogue and integration between different areas within the communication field. Our results indicate that the communication sphere becomes more identifiable and its knowledge more practical by redefining communication as a discipline of the science of meaning. Future communications studies should expand and change the direction of communication from the transmission of meaning to the design of meaning.